“Ghostbusters: Afterlife” is the front runner at the domestic box office, as the comedy sequel is headed towards a $40.5 million haul for the weekend.After earning $4.5 million in Thursday previews, “Afterlife” was originally projected to draw a three-day total of $27 million to $30 million, a figure that the film is now outperforming. The Sony Pictures release grossed $16.5 million from 4,315 locations on Friday.Sony has positioned the comedy sequel for continuous play over the U.S. Thanksgiving holiday next weekend, betting on great word-of-mouth to earn ticket sales from families of men, women and children. During the pandemic era, young adults have been the primary audience to show interest in returning to theaters, while family and adult-oriented films have failed to draw big numbers more often that not. How “Afterlife” holds over the next few weeks remains up in the air, though its “A-” CinemaScore is certainly an encouraging sign of enthusiasm from audiences....<p><a target="_blank" href=http://imdb.com></a></p>